Developing Informatics Infrastructure for High-Quality Medical Evidence in the Era of Precision/Personalized Medicine

The precision/personalized medicine era has brought about a growing need for high-quality, reliable, transparent, and updated medical evidence. Physicians rely on the latest evidence to tailor patient care and improve outcomes. However, obtaining such evidence can be challenging, especially when dealing with complex medical conditions and treatments.

That's where Nucleati comes in. As a leader in developing informatics infrastructure for healthcare organizations and researchers, Nucleati works closely with clients to understand their needs and current curation systems, if any. They then combine this knowledge with their expertise to develop a customized infrastructure that supports the entire workflow, from evidence searching to releasing and updating.


At the heart of Nucleati's approach is a commitment to producing high-quality medical evidence that is reliable, transparent, and unbiased. To achieve this, they offer a range of intermediate steps that help ensure the evidence is of the highest quality. These include:

  1. Supporting evidence categorization: Researchers can better understand the relationships between different studies and findings by organizing evidence into meaningful groups.
  2. Adding supporting documents: Additional context and clarity can be provided by adding supporting documents to the evidence.
  3. Field extraction or capture: Identifying key data points from the evidence can help researchers draw meaningful conclusions.
  4. Summary generation: Distilling the most important information from the evidence can help busy healthcare professionals quickly grasp the key findings.
  5. Guideline-based weighing: Evaluating the strength of evidence according to established guidelines can help ensure that it is reliable and trustworthy.
  6. Independent and consensus scoring for evidence strength: A rigorous evaluation process can ensure that the evidence is unbiased and objective.
  7. Inference generation: Drawing meaningful conclusions from the evidence can inform patient care and improve outcomes.

By offering these intermediate steps, Nucleati can help healthcare organizations and researchers produce, store, and distribute high-quality, reliable, transparent, and updated medical evidence. The resulting informatics infrastructure streamlines the entire workflow, making it easier to access and use the evidence in clinical practice.

Overall, Nucleati's approach to developing informatics infrastructure is well-suited to healthcare organizations and researchers who require high-quality medical evidence in the precision/personalized medicine era. By combining their own expertise with the specific needs of each client, Nucleati is able to produce customized solutions that support the entire workflow and ensure that the evidence is of the highest quality. The result is improved patient outcomes and better healthcare for all.

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